I was giving my spaniel the individual ingredients in this product twice a day. This involved quite a few supplements, so when I came across this product (I have used other Thorne Research products in my practice) I was excited to simplify our regimen a bit. I still give Violet additional C0 Q 10 and L- taurine, and add fish oil to her regimen, but dosing this once a day has simplified our regimen significantly. She is taking this for a worsening murmur, stay tuned. It may take months or longer to tell if it's working. I plan to keep her on it as a preventative even if the heart murmur does not change . The caps are a bit generous in size, I just open them up and put on her food, she takes it without any problem.