When I started to use Pancreatin to help me with my digestion, I tried various brands and finally settled on the Twinlab Pancreatin. Twin lab Pancreatin worked well for me, and I relied on it completely and have used it for several years. Lately, the product does not seem as effective as it used to. The reason could also be due to changes in my digestion condition. I will need to try out other makers products to a certain if Twinlab Pancreatin has become unsuitable for me. The rating I gave is based on current experiences.